ACADEMIC STAFF (PS)

1. UN SDG ที่เกี่ยวข้อง : SDG 3 “Inhibitory effect of Zingiber cassumunar Roxb. (Phlai) on nasal cytokine productions and eosinophilic recruitment in patients with allergic rhinitis” Allergic rhinitis (AR) is chronic upper respiratory tract disease which affects quality of life. AR exhibits inflammatory response in the nasal mucosa characterized by activation of mast cells, eosinophils and T-lymphocytes. Zingiber cassumuunar Roxb. (Phlai) has been used for the treatment of allergies including AR since it has anti-histamine effect but the assessment of nasal cytokine and eosinophil production has not been investigated. This study was a randomized, double-blinded examination. We found that AR patients received Phai for 2 weeks exhibited reductions in IL-5, IL-13 and number of eosinophils in nasal secretion, and reduced in total nasal symptoms scoring while there were no significant differences in all nasal cytokines, eosinophil counts in subjects received placebo. Phai is a promising herbal medicine for alleviating inflammation and AR symptoms.